PDK3 Antikörper
Kurzübersicht für PDK3 Antikörper (ABIN1539888)
Target
Alle PDK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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Immunogen
- Purified His-tagged PDK3 protein(Fragment) was used to produced this monoclonal antibody.
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Isotyp
- IgG2b
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anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 174-263) antibody
PDK3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2B11 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB23090 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 1-30), (N-Term) antibodyPDK3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB3039 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 174-263) antibodyPDK3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3A1 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 137-406) antibodyPDK3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (Center) antibodyPDK3 Reaktivität: Human ICC, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (N-Term) antibodyPDK3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 131-362) antibodyPDK3 Reaktivität: Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:100~800
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- PDK3 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Haltbarkeit
- 6 months
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- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
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Andere Bezeichnung
- PDK3
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Hintergrund
- The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
- 46939
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Gen-ID
- 5165
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NCBI Accession
- NP_001135858, NP_005382
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UniProt
- Q15120
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Pathways
- PI3K-Akt Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
Target
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